Szemészet, 2006 (143. évfolyam, 1-4. szám)
2006-12-01 / 4. szám
143. évfolyam (2006) Supplementum I. No■> 47 Alterations in corneal and scleral thickness in different eye diseases Tamás Gyetvai, Ákos Skribek, Lajos Kolozsvári University of Szeged Faculty of Medicine, Department of Ophthalmology Alteration in the corneal and/or scleral thickness can occur without symptoms, but it can sometimes cause problems including visual disturbance, uveal bulging, or perforation. Our aim is to survey these aspects by presenting different cases. Ultrasound biomicroscopy can play a role in the diagnosis and differential diagnosis, and also in followup examinations. Photodynamic therapy with low-dose Verteporfin for persistent neurosensory detachment in patients with central serous chorioretinopathy Anton Haas, Georg Mossböck, Christian Stangl, Richard Maier, Christina Wohlfart, Martin Weger Medical University of Graz (Austria), Department of Ophthalmology Purpose: to demonstrate the efficacy of photodynamic therapy (PDT) using a reduced dose of verteporfin in treating patients with central serous chorioretinopathy (CSC) and persistent neurosensory detachment. Methods: Thirteen eyes of 13 consecutive patients were treated. The eyes had had CSC and persistent neurosensory detachment involving the central macula for at least 6 months, and had active leaks as documented by optical coherence tomography (OCT) as well as by fluorescein angiography (FA) and indocyanine green angiography (ICGA). Patients received PDT with a reduced dose of verteporfin (dose: 3 mg/m^ body surface area; followed by retinal application of 50 J/cm2 of 689 nm laser light). Results: The follow-up time ranged between 6 and 17 months (median 9.7 months). The visual acuity improved by two or more lines in 7 eyes (54%), and remained stable in 5 eyes (38%). Acuity decreased in the remaining patient (8%), due to retinal pigment epthelium (RPE) atrophy. The mean visual acuity improvement was 1.4 lines, and was statistically significant (p < 0.01). Nine eyes (69%) had a complete, and 4 (31%) an incomplete, anatomic resolution of the subretinal fluid, as revealed by the OCT. Fluorescein leakage disappeared completely in 9 eyes (69%), while residual leakage was found in 3 eyes (23%), and active leaks in one eye (8%). Conclusion: Our pilot study demonstrates that photodynamic therapy with a low dose of verteporfin appears to have a beneficial effect in treating patients with CCS and persistent neurosensory detachment by reducing fluid leakage and subretinal fluid accumulation. The pathology causing CSC has shifted from the RPE level to haemodynamic disturbances at the choroidal level. PDT with half the normal dose of verteporfin seems to be sufficient to affect the choroidal blood flow and to decrease fluid passage towards the retina. A vitreoretinalis határfelszín vizsgálata senilis macula degeneratioban Hargitai Zsófia,1 Mirk Éva,2 Récsán Zsuzsa1 Semmelweis Egyetem, Mária utcai Szemészeti Klinika, Budapest 2Semmelweis Egyetem, V éves orvostanhallgató, Budapest Klinikai megfigyelés: A senilis macula degeneratioban (AMD) szenvedő ugyanazon beteg két szeme között lényeges különbség lehet.
