200795. lajstromszámú szabadalom • Eljárás többszörös horgokat tartalmazó plazminogén aktivátorok előállítására
HU 200795 B Int Cl5 C 12 N 15/58 A 61 K 37/54 "A" példa folytatása 901 911 921 931 941 951 ACTGCCGGAATCCTGATGGGGATGCCAAGCCCTGGTGCCACGTGCTGAAGAACCGCAGGC CysArgAsnProAspGlyAspAlaLysProTrpCyshisValLeulysAsnArgArgLeu 961 971 961 991 1001 1011 T GACGT GGGAGT ACTGTGATGT GCCCTCCT GCTCCACCTGCGGCCT GAGACAGTACAGCC ThrTrpGluTyrCysAspValProSerCysSsrThrCysGlyLeuArgGlnTyrSerGln 1021 1031 1041 1051 1061 1071 AGCCTCAGTTTCGCATCAAAGGAGGGCTCTTCGCCGACATCGCCTCCCACCCCTGGCAGG ProGlnPheArglleLysGlyGlyLeuPheAlaAspIleAIaSerHisProTrpGlnAla 1081 1091 1101 1111 1121 1131 -CTGCCATCTTTGCCAAGCACAGGAGGTCGCCCGGAGAGCGGTTCCTGTGCGGGGGCATAC AlallePheAlaLysHisArgArgSsrProGlyGluArgPheLeuCysGlyGlylleLeu 1141 1151 1161 1171 1181 1191 TCATCAGCTCCTGCTGGATTCTCTCTGCCGCCCACTGCTTCCAGGAGAGGTTTCCGCCCC IleSerSerCysTrpIleLeuSerAlaAlaHisCysPheGInGluArgPheProProHis 1201 1211 1221 1231 1241 1251 ACCAGCTGACGGTGATC7TGGGCAGAACATACCGGGTGGTCCCTGGCGAGGAGCAGCAGA HisleuThrValIleLeuGlyArgThrTyrArgValValProGlyGluGluGluGlnLys 1261 1271 1281 1291 1301 1311 AATTTGAAGTCGAAAAATACATTGTCCATAAGGAATTCGATGATGACACTTACGACAATG PheGluValGluLysTyrlleValHisLysGluPheAspAspAspThrTyrAspAsnAsp 1321 1331 1341 1351 1361 1371 AGAITGCGCTGCTGCAGCTGAAATCGGATTCG1CCCGCTGTGCCCAGGAGAGCAGCG1GG IleAlaLeuLeuGlnLeuLysSerAspSerSarArgCysAlaGlnGlüSerSerV'alVal 1381 1391 1401 1411 1421 1431 TCCGCACTGTGTGCCTTCCCCCGGCGGACCTGCAGCTGCCGGACTGGACCGAGTGTGAGC Ai’gThrValCysLeuProProAlaAspLeuGlnLeuProAspTrpThrGlüCysGluLeu 1441 1451 1461 1471 1481 1491 TCTCCGGCTACGGCAAGCATGAGGCCTTGTCTCCTTTCTATTCGGAGCGGCTGAAGGAGG SerGlyTyrGlyLysHisGluAlaLeuSerProPheTyrSerGluArgLeuLysGluAla 1501 1511 1521 - 1531 1541 1551 CTCATGTCAGaCTGTACCCATCCAGCCGCTGCACATCACAACATTTACTTAACAGAACAG HisValArgLeuTyrProSerSerArgCysThrSsrGlnHisLeuLeuAsnArgThrVal 1561 1571 1581 1591 1601 1611 TCACCGACAACATGCTGTGTGCTGGASACACTCGGAGCGGCGGGCCCCAGGCAAACTTGC ThrAspAsnMetLeuCysAlaGlyAspThrArgSerGlybiyProGlnAlaAsnLeuHis 1621 1631 1641 1651 1661 1671 ACGACGCCTGCCAGGGCGAT 7CGGGAGGCCCCCT GGTGTGTCT GAACGAT GGCCGCAT GA AspAlaCysGlnGlyAspSerGlyGlyProLeuValCysleuAsnAspGlyArc/'ietThr 1681 1691 1701 1711 1721 1731 CTTTGGTGGGCATCATCAGGTGGGGCCTGGGGTGTGGACAGAAGGATGTCCCGGGTGTGT LeuValGlyllelleSerTrpGlyLeuGlyCysGlyGlrlysAspValProGlyValTyr 1741 1751 1761 1771 1781 1791 ACACAAAGGTTACCAACÍACCTAGACTGCATTCGTGACAACATGCGACCGTGACCAGGAA ThrLysValThrAsnTyrLeuAspTrpIleArgAspAsnMetArgProTER 1801 1811 1821 1831 CACCCGACT CCT CAAAAGCAAATGAGAT CCGGAT CC 9.a ábra
