191378. lajstromszámú szabadalom • Eljárás vinil-tio-acetamido-oxa-cef-3-ém-4-karbonsav-származékok előállítására

III. táblázat folytatása

vegy ulet u v w x y 7 IR NMR

szama

2H), 4,67 (s, 2H),

5,07 (s, 1H), 6,92 (s, 1H), 7,26-7,61 (m, 11H)

3-28

11 -CN CM-scn3

CH

!

iTctCH,

CHC!3:

CDClj :

Ph,

3530,3360, 2200, 1785, 1715,1630,

7,2—7,6 (m, 10H).

6.83 (s, í FI), 5,00 (s, 3H), 4,58 (s, 2H), 4,20 (s, 2H),

3.83 (s, 2H), 3,75 (s, 311), 3,52 (s, 3H), 2,57 (s, 3H)

3-29

H Cl 11

Cl

Cll

1-STelCHj

CHCI3 :

CDCI3 :

1

Ph3

3350,1785,

1700

3,55 (s, 3H), 3,70 (s, 2H), 3,77 (s, 3H), 4,23 (s, 2H), 4,62 (s, 2H), 5,05 (s, 1H), 647 (s, 1H), 6,90 (s, 1H), 7,10-7,67 (in, 11H)

3-30

Pb H H

Cl-CH

1

■ST.:tCH3

CDC13:

1

Pha

3,50 (s,3H), 3,83 (s, 3H), 4,28 (s, 2H), 4,61 (s,2H), 4,90 ('s, 1H), 6,13 (d, 1H, J = 7), 6,47 (d,lH,J = 7),

6,95 (s, 1H), 7,17— 7,70 (m, 15H)

3-31-CO II H

1

Cl-CH

1

HiCIl.,

CHC13:

CDC!3 :

NHj

!

Ph2

1790,

1710,

1695

3,55 is, 3H), 3,80 (s, 3H), 4,28 (bs 2H), 4,47 (s, 1H), 4,63 (d, 1H, J = 6,5), (6,92, s, 1H), 7,07-7,67 (m, 12H), 8,53 (bs, 1H)

3-32-CO H H 1

Cl-CH

1-STítCHj

CDC13-'

30

OtBU

Phj

1,50 (s, 9H), 3,58 (s, 3H), 3,85 (s, 3H), 4,20 (s, 1H), 4,27 (s, 2H), 4,63 (s, 2H), 5,07 (s, 1H), 6,15 (d, 1H„

J = 7), 6,58 (d, 1H, J = 7), 6,92 (s, 1H), 7,26-7.66 (m, 10H)