191378. lajstromszámú szabadalom • Eljárás vinil-tio-acetamido-oxa-cef-3-ém-4-karbonsav-származékok előállítására

19 378

Hl. táblázat folytatása

Vegyület u v w x y z IR NMR

száma

3-10 H H H Cl -CH

I

Ph2

3-11 H H M Cl Cl 1

I

Ph2

3-12 H H H Cl -CM

t

Ph2

3—13 H H H Cl -CH

I

STeíCHjCHí CHC13: CDC13:

I

sl^CH -NH 3350,1785, 3,35-3,82 (m, 4H j,

1710,1695 3,55 (s,3H), 4,05-4,48 (m, 4H), 4,48- 4,75 (m, 2H). 5,08 (s, 1H), 6,13 (d,

1H, J =7), 6,48 (d,

1H,J = 7), 6,47- 6,97 (ni, 2H), 6,88 (s, 1H), 7,20-7,87 (m, 11H), 8,03 (bs, 1H)

8Ï! tCMjCMjNH 1

C11CI3:

CDC13:

tBuOCO

3440,3350, 1785, 1705

1,35 (s, 9H), 3,27- 3,67(m, 4H), 3,52 (s, 3H), 4,07)-4,40 (m, 4H), 4,50-4,77 (m, 2H), 5,07 (s, 1H), 5,03-5,37 (rn, 1H), 6,07 (d, 1H, J = 7), 6,47 (d, 1H, J = 7), 6,85 (s, 1H), 7,13— 7,77 (m, 11H)

STc CHjCH2 1

CHCI3:

CDC13:

N(CH3)í

3370,1795, 1700

2.18 (s, 6H), 2,68(1, 2H, J = 6), 3,45 (s, 2H), 3,53 (s, 3H),

4.18 (t, 2H,J =6), 4,23 (bs, 2H), 4,62 Cos, 2H), 5,03 (s, 1H), 6,87 (s, 1H), 7,15-7,6 (m,

UH)

STetCHjCHjOH

CHC13:

CDC13 :

3350,1780, 1705

3,45 (bs, 2H), 3,55 (s, 3H), 3,80-4,37 (m, 6H), 4,58 (bs, 2H), 5,03 (s, 1H), 6,12 (d, 1H, J = 7), 6,38 (d, 1H, J = 7), 6,87 (s, 1H), 7,10-7,63 (m, UH)

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