191378. lajstromszámú szabadalom • Eljárás vinil-tio-acetamido-oxa-cef-3-ém-4-karbonsav-származékok előállítására

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III. táblázat folytatása

Vegyület u v w x y z IR NMR

szama

3-14 H H H Cl

3-15 H H H Cl

3-16 H H H Cl

3-17 H H H Cl

~CH -STeiCHjCHj

I !

Ph2 OCII3-CH

1-STetCH2CII2 OCO 1

1

Ph2

1

UCII

CH

1

-STetCH2 CH2 OCO 1

Ph2

1

C12CH-CH -STetCHjCHjO

1 I

Ph2 PhCH, OCO

CHCISl:

CDCI3 :

3350,1780,

3,27 (s, 311), 3,47

1710,1700

(bs, 3H), 3,55 (s, 3H), 3,70 (t, 2H,

J = 5), 4,62 (s, 2H), 5,05 (s, 1H), 6,12 (d, 1H, J = 7),

6,37 (d, 1H, J = 7), Ç,88 (s, III), 7,10-7,67 (m, 11H)

Aceton-d6 :

3,53 (s, 3H), 3,57 (s, 2H), 4,13 (s, 2H), 4,31 (s, 2H), 4,58 (s,4H), 4,68 (s, 2H), 5,10 (s, 1H), 6,21 (d, 1H,

J =7), 6,73 (d, 1H, J = 7),6,92 (s, 1H), 7,2-8,25 (m, 1 OH), 8,16 (s, 1H)

CHCI3:

CDCI3 :

3690,3370,

3,45 (s, 2H),: 3,57 (s,3H),

1790,1702,

4,27 (s, 2H),

1631

4,47 (t, 2H, J = 5),

op:172cC

4,53 (t, 2H, J = 5), 4,63 (s, 2H) 5,05 (s, 1H), 5,87 (s, 1H), 6,13 (d, 1H,

J = 6), 6,37 (d, 1H, J = 6), 6,90 (s, 1H), 7,20-7,60 (m, 11H)

CHCI3 :

CDCI3 :

3370,1791

7,2-7,7 (m, 10H),

1751,1702,

6,86 (s, 1H), 6,37

1631,1602,

(d, 1H,J = 6), 6,12

op: 80-87 °

C (d, 1H. J = 6), 5,07

(s, 2II), 5,03 (s, 1H), 4,57 (s, 2H), 4,41 (s, 4H),4,2(s,2H), 3,53 (s. 3H), 3,42 (s,2H).

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