191378. lajstromszámú szabadalom • Eljárás vinil-tio-acetamido-oxa-cef-3-ém-4-karbonsav-származékok előállítására

Í9i ii8

II. táblázol folytatása

Vegyidet u v w x y i IR NMR

szama

2-69 H H -CONHj F Na ~STetCH,CONH

!

CHj

KBr: D20:

3400. 1770, 3,25 (s, 3H), 3,97 (s, H),

1680, 1610 4,15 (s. 2H), 4,57-4,73 (m,

2H), 4,75 (bs,2H), 5,60,

(s, 1H), 5,67 (s, 2H), 7,73 (d, 1H,J = 34)

2-70 H H -CONHCM3 F Na SI ïtCH2CH2OH

D20:

3,25 (s, 3H\ 3,97 (s, 3H),

4,13 (s, 2H), 4,33-4,73 (m, 4H), 4,87-5,03 (m, 411), 5,58 (s, 1H), 7,25 (d, 1H, J = 34)

2-71 H H H F Na -STetCH2CH2CONH

KBr:

3400,1768,

1665,1610

2-72 H H H F Na

2-73 H H H F Na

CH3

KBr: D20:

3340. 1767, 3,28 (s, 3H), 4,00 (s, 5H),

1678, 1610 4,68 (bs,2H), 5,00 (bs,2H),

5,65 (s, 1H), 5,70 (s, 2H),

6,08 (dd, 1H, J =4,40),

7,36 (dd, 1H, J = 4,82)

■ST iCH2CH2OH KBr:

3420,1770, 1685,1610

3TrítCH2CONH2

KBr:

3400,1766, 1688, 1630 (sh) 1606

D20:

3.95 (s, 5H), 4,22-5,07 (m 8H),

5,60 (s, 1H). 6,08 (dd, 1H,

J = 4,40 ), 7,28 (dd, 1H,J = 4,82)

D20:

3,63 (s.SH), 4,57-4,70 (m,

2H). 4,95 (bs, 2H), 5,25 (s, 1H),

5.38 (s,2H), 6,03 (dd, 1H,

J =4,40), 7,28 (dd, 1H, J =4,81)

2-74 H H H F Na -SínCH2CONH

I

HOCHiCH,

KBr: D20:

3380, 1767, 3,95 (s, 5H), 3,68-4,25

1678, 1630 (m, 4H), 4,53-4,70 (m, 2H),

(sh) 1605 4,93 (bs, 2H), 5,58 (s, 1H),

5,70 (s, 211), 6,03 (dd, 1H,

J = 4,40), 7,28 (dd, 1 H, J = 4,82)

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