Szemészet, 2010 (147. évfolyam, 1-4. szám)
2010-12-01 / 3-4. szám
147. évfolyam (2010) Supplementum I. 73 Systemic mycophenolate mofetil therapy for highrisk perforating keratoplasty patients Ildikó Süveges Semmelweis University, Budapest, Department of Ophthalmology Introduction: Mycophenolate mofetil (MMF) is an effective immuno-suppressive therapy for patients with high-risk perforating keratoplasty (PKP). Material and methods: 12 PKP patients were treated with MMF. 10 cases were at high risk of a second or repeated PKPs and/or deep vascularisation in more than one quadrant. Since this condition had been present already at the time of the surgery, MMF therapy was started on the day of the surgery. In 2 cases rejection reaction occurred after a complication-free wound-healing process of 6 and 18 months, respectively. In 3 patients with PKP because of HSV infection, therapy against systemic herpes was applied in addition to MMF. The therapy in all cases included treatment with corticosteroids. The follow-up time ranged between 5 and 18 months. Results: In 8 cases no rejection occurred postoperatively, the graft remained crystal-clear. In 2 cases the cornea was found semi-transparent after a week following the surgery, showing no improvement at the end of the follow-up period either. Two late rejections were successfully prevented by MMF. Conclusion: The use of MMF is helpful in preventing both early and late rejection reactions. The therapy for HSV- infected patients has to be combined with systemic antiherpetic agents. A Young-Helmholz-elmélet és a csapok metrikus mérete Szabó György A retinalis képpont (humán pixel) mérete a hullámhossz és a pupillatágasság függvénye. Az átlagos pixelátmérő 3-5 mikrométer, a csapoké 2-4 közötti. A Young-Helmholz-elmélet szerint a színes fénysugárnak (retinalis pixelnek) legalább három csapfelszínt kell lefednie, hogy a helyes színérzést létrehozza. A pixelek átlagban 12,5 (7-20-ig) négyzetmikrométert hoznak létre, három csap felszíne pedig 21 (10-től 36-ig) négyzetmikrométert tesz ki. Összevetve a fenti metrikus értékeket, a három csap színelmélet nem tűnik elfogadhatónak. The Young-Helmholz theory and the metrical size of cones György Szabó The size of the human retinal pixel depends on the wavelenghts of light and the diameter of the pupil. On average this value lies between 3-5 micrometers. The diameter of the retinal cones lies between 2-4 micrometer, as well. According to the Young-Helmholz theory some colourful ray i.e. the retinal pixel beam has to cover at least minimally three cones to determine the adequate color sense. The surface of a pixel represents on average 12.5 (from 7 to 20) square micrometers, while the surface of three cones represents 21 (from 10 to 36) square micrometers. Comparing the above metrical facts it seems impossible to accept the three cones colour sense theory. Elő adáski vonatok / Abstracts
