Szemészet, 2006 (143. évfolyam, 1-4. szám)
2006-12-01 / 4. szám
78 Szemészet Supplementum I. 4) Dr. Módis László: Endothelium és spekulár mikroszkópia (DEOEC, Szemészeti Klinika, Debrecen), 5) Dr. Imre László: Konfokális mikroszkópia (SE, Szemészeti Klinika, Budapest), 6) Dr. Losonczy Gergely: Molekuláris genetika, szövettan (DEOEC, Szemészeti Klinika, Debrecen) Minden előadás 15 perces. The diagnostics of corneal diseases László Módis University of Debrecen, Department of Ophthalmology This thematically-related series of lectures given by lecturers experienced in the topic reviews the conventional and modern diagnostic methods for corneal diseases. In everyday practice, in our fast-moving world classic methods such as evaluation of clinical history and appearance under slitlamp examination seem to be superseded. The first lecture summarises this question. The second presentation gives an overview on the cornea and anterior segment with help of ultrasound biomicroscopy (UBM). For precise diagnosis, planning of surgery, and judgement of the efficacy of therapy an exact knowledge of the anterior and posterior corneal surface - refractive power and endothelium - is practically essential. These are investigated with corneal topography and specular microscopy. Indications, methods of examination, and evaluation of the results are discussed during the third and fourth lecture. The investigation of all corneal layers in vivo at histological level can be performed with the help of confocal imaging techniques. The fifth lecture presents examples of normal and pathologic corneas as seen with the Confoscan instrument. Molecular genetics are nowadays practically part of routine diagnostics. The last talk reviews those mutations causing corneal dystrophies, and presents their histological structure. Lecturers: 1) Prof. Dr. Ildikó Süveges: Clinical history and clinical picture (Semmelweis University, Budapest, Department of Ophthalmology) 2) Prof. Dr. Lajos Kolozsvári: Ultrasound biomicroscopy (UBM) (University of Szeged, Department of Ophthalmology) 3) Dr. Agnes Kerényi: Corneal topography (Bajcsy-Zsilinszky Hospital, Budapest) 4) Dr. László Módis: Endothelium and specular microscopy (University of Debrecen, Department of Ophthalmology) 5) Dr. László Imre: Confocal microscopy (Semmelweis University, Budapest, Department of Ophthalmology) 6) Dr. Gergely Losonczy: Molecular genetics, histology (University of Debrecen, Department of Ophthalmology) Each lecture lasts 15 minutes. Impact of dose-rate on the clinical course following brachytherapy with ruthenium-106 G. Mossböck, T. Rauscher, M. Schmutzer, W. Wackernagl, G. Langmann Medical University of Graz (Austria), Department of Ophthalmology Brachytherapy with ruthenium-106 (BTR) is an established eye-preserving therapy for small to medium-sized uveal malignant melanomas. However, few studies have analysed the impact of the dose rate on the clinical course following BTR. We therefore performed a retrospective study including 45 patients who received BTR at our Department. Two groups receiving distinct dose rates were compared: group 1. (25 patients), with a dose rate below 4 G/h, and group 2. (20 patients), with a dose rate of at least 4 G/h. Mean tumour height in the two groups was 5.2mm and 5.5mm respectively. After mean follow-up times of 61.3 and 63.2 months respectively, we found that early and late complications were more common in group 2.; but the difference was without statistical significance. Local tumour control and rate of recurrence were similar in both groups. In group 1. five patients developed metastases, while in group 2 no patient
