202278. lajstromszámú szabadalom • Eljárás fokozott stabilitású, rekombináns gamma-interferonok és ezeket tartalmazó gyógyszerkészítmények előállítására
HU 202278 B Int CI5 C 12 N 15/23 C 12 P 21/02 A 61 K 37/02 1. ábra TGAAGATCAGCTATTAGAAGAGAAAGATCAGTTAAGTCCTTTGGACCTGATCAGCTTGATACAAG 50 sl met lys tyr thr AACTACTGATTTCAACTTCTTTGGCTTAATTCTCTCGGAAACG ATG AAA TAT ACA ICO Bér AGT 810 tyr ile leu ala phe gin leu cys ile val leu gly ser leu TAT ATC TTG GCT TTT CAG CTC TGC ATC GTT TTG GGT TCT CTT lFO s23 1 10 gly cys tyr cys GLN ASP PRO TYR VAL LYS GLU ALA GLU ASN LEU LYS GGC TGT TAC TGC CAG GAC CCA TAT GTA AAA GAA GCA GAA AAC CTT AAG 20 LYS TYR PHE ASN ALA GLY HIS SER ASP VAL ALA ASP ASN GLY AAA TAT TTT AAT GCA GGT CAT TCA GAT GTA GCG GAT AAT GGA 2$0 30 40 THR LEU PHE LEU GLY ILE LEU LYS ASN TRP LYS GLU GLU SER ASP ARG ACT CTT TTC TTA GGC ATT TTG AAG AAT TGG AAA GAG GAG AGT GAC AGA 3*0 50 LYS ILE MET GLN-SER GLN ILE VAL SER PHE TYR PHE LYS LEU AAA ATA ATG CAG AGC CAA ATT GTC TCC TTT TAC TTC AAA CTT 60' PHE LYS ASN PHE LYS ASP ASP GLN SER ILE GLN LYS TTT AAA AAC TTT AAA GAT GAC CAG AGC ATC CAA AAG 350 80 ILE LYS GLU ASP MET ASN VAL LYS PHE PHE ASN SER ASN LYS ATC AAG GAA GAC ATG AAT GTC AAG TTT TTC AAT AGC AAC AAA 4*0 90 110 LYS LYS ARG ASP ASP PHE GLU LYS LEU THR ASN TYR SER VAL THR ASP AAG AAA CGA GAT GAC TTC GAA AAG CTG ACT AAT TAT TCG GTA ACT GAC 4*0 110 LEU ASN VAL GLN ARG LYS ALA ILE HIS GLU LEU ILE GLN VAL TTG AAT GTC CAA CGC AAA GCA ATA CAT GAA CTC ATC CAA GTG 5*0 70 SER”VAL GLU THR AGT GTG GAG ACC
