201564. lajstromszámú szabadalom • Eljárás dipeptid renin inhibitorok előállítására
7 HU 201564 B 8 NMR (60 MHz) X Y Rí R2 Rs delta (CD3OD) H H CsHn-C=CH2 CHs 2,7 (3H, s), 5,5 ér (2H, m), 7,0-8,0 (5H, m) 5-C1 H CsHn-CH=CH CH3 2,7 (3H, s), CH2 N3 7,0-8,0 (4H, m) 5-C1 H CsHn-CH-CH3 CH3 1,1 (3H, d, J=5Hz), ÓH 2,7 (3H, s), 7,0-8,0 (4H, m) 5-C1 H CsHn-CH=CH CH3 2,7 (2H, m), 5,6-6,7 Ól (2H, m) 7,0-8,0 (4H, m) 5-C1 H CsHn CH=C(CH3)2 CH3 1,8 (6H, sz.‘ s), 2,7 (3H, s), 7,0-8,0 (4H, m) 3-C1 H CsHn /-C3H? CH3 0,95 (6H, d, J=5 Hz), 2,7 (3H, s) 5-C1 H CsHn-C=CH2 CH3 2,7 (3H, s), 5,5 (2H, m), ér 7,0-8,0 (4H, m) 5-C1 H CsHn Í-C3H7 CH3 0,95 (6H, d, J=5 Hz), 2,4 (3H, s), 2,7 (3H, s), 7,0-8,0 (4H, m) 5-C1 H CsHn CH2CHC2H5 CH3 0,95 (12H, ra), 2,7 CH3 (3H, s), 7,0-8,0 (4H, m) *sz.= széles 5-C1 H CsHn-CH=CH2 H 2,7 (3H, s), 4,95 (2H, m), 7,0-8,0 (4H, m) 5-C1 H CsHn-CsHs CH3 2,7 (3H, s), 7,0-8,0 (9H, m) H H CsHn Í-C3H7 CH3 0,95 (6H, d, J=5Hz), 2,7 (3H, s), 7,0-8,0 (5H, m) 5-F H CsHn Í-C3H7 CH3 0,95 (6H, d, J=5 Hz), 2,7 (3H, s), 7,0-8,0 (4H, m) H H CsHn-CH=CH2 CH3 2,7 (3H, s), 4,95 (2H, m), 7,0-8,0 (5H, m) 5-C1 H CsHn-CH=CHC1-(CH2)2N 0 2,6 (6H, m), 5,15 (2H, m), 6,9-7,7 (4H, m) 5-C1 H CsHn-CH=CHCH3 CHs 1,6 (3H, m), 2,7 (3H, s), 6,9-7,7 (4H, m) 5-C1 H CsHn-CH=CHCH3 -(CHz)2N^JD 1,6 (3H, m), 2,6 (6H, m), 5,3-5,7 (2H, m) 5-C1 H CsHn Í-C3H7-(CHDÍH^O 0,95 (6H, d, J=5Hz), 2,7 (3H, s), 6,9-7,7 (4H, m) 6
