200795. lajstromszámú szabadalom • Eljárás többszörös horgokat tartalmazó plazminogén aktivátorok előállítására
HU 200795 B Int Cl5 C 12 N 15/58 A 61 K 37/54 901 911 921 911 941 951 ctctgagggaaacagtgact gct act ttgggaatgggtcagcct accgtggcacgcacag SerGluGlyAsnSerAspCysTyrPheGlyAsnGlySerAlaTyrArgGlyThrHisSer 961 971 981 991 1001 1011 CCTCACCGAGTCGGGTGCCTCCTGCCTCCCGTGGAATTCCATGATCCTGATAGGCAAGGT LeuThrGluSerGlyAlaSerCysleuProTrpAsnSerMetlleLeuIleGlylysVal 1021 1031 1041 1051 1061 1071 TTACACAGCACAGAACCCCAGT GCCCAGGCACTGGGCCTGGGCAAACAT AATTACT GCCG TyrThrAlaGlnAsnProSerAlaGlnAlaLeuGlyleuGlyLysHisAsnTyrCysArg 1081 1091 1101 1111 1121 1131 GAATCCTGATGGGGATGCCAAGCCCTGGTGCCACGTGCTGAAGAACCGCAGGCTGACGTG AsnProAspGlyAspAlalysProTrpCysHisValLeulysAsnArgArgLeuThrTrp 1141 1151 1161 1171 1181 1191 GGAGTACTGTGATGTGCCCTCCTGCTCCACCTGCGGCCTGAGACAGTACAGCCAGCCTCA GluTyrCysAspValProSerCysSerThrCysGlyLeuArgGlnTyrSerGlnProGln 1201 1211 1221 1231 1241 1251 GTTTCGCATCAAAGGAGGGCTCTTCGCCGACATCGCCTCCCACCCCTGGCAGGCTGCCAT PheArglleLysGlyGlyLeuPheAlaAspIleAlaSerHisProTrpGlnAlaAlalle 1261 1271 12B1 1291 • 1301 1311 CTTTGCCAAGCACAGGAGGTCGCCCGGAGAGCGGTTCCTGTGCGGGGGCATACTCATCAG PheAlalysHisArgArgSerProGlyGluArgphsLeuCysGlyGlylleLeuIleSer 1321 1331 1341 1351 1361 1371 CTCCTGCTGGATTCTCTCTGCCGCCCACTGCTTCCAGGAGAGGTTTCCGCCCCACCACCT SerCysTrpIleLeuSerAlaAlaHisCysPheGlnGluArgPheProProHisHi5Leu 1381 1391 1401 1411 1421 1431 GACGGTGATCTTGGGCAGAACATACCGGGTGGTCCCTGGCGAGGAGGAGCAGAAATTTGA ThrValIleLeuGlyArgThrTyrArgValValProGlyGluGluGluGlriLysPheGlu 1441 1451 1461 1471 1481 1491 AGTCGAAAAATACATTGTCCATAAGGAATTCGATGATGACACTTACGACAATGACATTGC ValGluLysTyrlleValHisLysGluPheAspAspAspThrTyrAspAsnAspIleAla 1501 1511 1521 1531 1541 1551 GCTGCIGCAGCTGAAATCGGATTCGTCCCGCTGTGCCCAGGAGAGCAGCGTGGTCCGCAC LeuleuGlnLeuLysSerAspSerSerArgCysAlaGlnGluSerSerValValArgThr 1561 1571 1581 1591 1601 1611 TGTGTGCCTTCCCCCGGCGGACCTGCAGCTGCCGGACTGGACGGAGTGTGAGCTCTCCGG ValCysLeuProProAlaAspleuGlnLeuProAspTrpThrGluCysGluLeuSerGly 1621 1631 1641 1651 1661 1671 CTACGGCAAGCATGAGGCCTTGTCTCCTTTCTATTCGGAGCGGCTGAAGGAGGCTCATGT TyrGlyLysHisGluAlaLeuSerProPheTyrSerGluArgLeuLysGluAlaHisVal 1681 1691 1701 1711 1721 1731 CAGACTGTACCCATCCAGCCGCTGCACATCACAACATTTACTTAACAGAACAGTCACCGA ArgLeuTyrProSerSerArgCysThrSerGlnH.isLeuLeuAsnArgThrValThrAsp 1741 1751 1761 1771 1781 1791 CAACATGCTGTGTGCTGGAGACACTCGGAGCGGCGGGCCCCAGGCAAACTTGCACGACGC AsnMetLeuCysAlaGlyAspThrArgSerGlyGlyProGlnAlaAsnLeuHÍ5AspAla 1801 IBII 1821 1831 1841 1851 CTGCCAGGGCGATTCGGGAGGCCCCCTGGTGTGTCTGAACGATGGCCGCATGACTTTGGT CysGlnGlyAspSerGlyGlyProLeuValCysLeuAsnAspGlyArc^etThrLeuVal 1B61 1871 1881 1891 1901 1911 GGGCATCATCAGCTGGGGCCTGGGCTGTGGACAGAAGGATGTCCCGGGTGTGTACACAAA GlyllelleSerTrpGlyLeuGlyCysGlyGlnlysAspValProGlyValTyrThrLys 1921 1931 1941 1951 1961 1971 GGTTACCAACTACCTAGACTGGATTCGTGACAACATGCGACCGTCACCAGGAACACCCGA ValThrAsnTyrLeuAspTrpIleArgAspAsnMetArgProTER 1981 1991 2001 CTCCTCAAAAGCAAATGAGATCCGGATCC 10.a ábra
