191378. lajstromszámú szabadalom • Eljárás vinil-tio-acetamido-oxa-cef-3-ém-4-karbonsav-származékok előállítására

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III. táblázat folytatása

Vegyület u v w x y 7_ IR NMR

száma

3-22 H H -CN Cl

3-23 H H -CH2 Cl I

OH

3-24 H H -CO Cl

I

NHj

3-25 H H -CO Cl

I

OCIlPh2

3-26 H H Cl Cl-CH

Plij-CH

Ph2-CH

I

Ph2-CH

I

Ph2-CH

!

Ph2-CH

I

Ph2-STetCH3-STetCHj-STetCHj-STetCH3-SretCIl,

STetCH,

CHCI3 :

CDCI3:

3370,2210, 1793,1703

3,51 (s, 5H), 3,75 (s, 3H) 423 (s, 2H), 4,65 (s, 2H), 5,07 (s, 1H), 6,92 (s, lH),7,2-7,5 (m, IOH), 7,70, (s, 1H)

CHCI3 :

CDCI3 :

3350,1780, 1717,1698,

3.42 (bs, 2H), 3,50 (s. 3H), 3,77 (s, 3H), 3,90-4,33 (m, 5H), 4,47-4,73 (m, 2H), 5,03 (s, 1H),

6.43 (bs, 1H), 6,87 (s, 1H), 7,2—7,6 (m, 12H), 7,87 (s, 1H), 9,25 (s, 1H)

Nujol:

DMSO-d6:

3260,1775, 1700,1635

3,45 (s, 3H), 3,70 (s, 311)3,72 (s, 2H), 4,22 (s, 2H), 4,40 (s. 2H), 5,15 (s, 1H), 6,87 (s, 1H 1H), 7,2-7,6 (m, 12H), 7,87 (d,

1H), 9,25 (s, 1H)

Nujol:

DMSO-d6:

3260,1780, 1705,1650,

3,35 (s, 3H), 3,43 (s, 2H), 3,83 (s, 4,18 (bs, 2H), 4,55 (bs, 2H), 5,20 (s, 1H), 6,95 (s, 1H), 7,3-7,8 (m,20H), 8,48 (s, 1H), 9,57 (s, 1H)

CHCI3:

CDCI3:

3350,1785, 1700

3,45 (s,2H),3,57 (s, 3H), 3,82 (s, 311), 4,27 (s,2H) 4,60 (s, 211), 5,08 (s, III), 6,88 (s, 1H), 7,22-7,67 (m, 11H)

CIICI3 :

CDCI3:

3360,1786, 1718,1678, mp: 110 °C

1,80-2,78 (m, 6H), 3,56 (s, 3H), 3,66 (s, H), 3,83 (s, 3H), 4,23 (s,

29

3-27

H -(CHj^CO- Cl