189715. lajstromszámú szabadalom • Eljárás 1-fenil- 1,8-naftiridin- és 1-fenil- 5-azaz-8-naftiridin-származékok előállítására

1

189 715

2

Vegyület

Y

Z

R1

r2

O.p. °C

száma

1

H

H-CH?CH?N(Ch3)?

HCl -só: 236-238

2

H

H

<CH?),CH,

CH9CH9CH9N(dl

3)2 HCl-sô: 197 199

3

H

H-ch2ch0h

H

233 234

4

H

H

■(Cn-j)^CH^-CH2CH2OH

136-138

5

H

H

<CH2)3CH2OH

H

♦1/6 CH3CH(0HX:H3

(szolvát) 205.5-206.5

6

H

H

<ch2)2ch2oh

H

218-220

7

H

H-CH2CH(0H)CH3

H

236-238

8

H

H-ch?ch=ch2-CHCH,

195-196

9

H

H

O (ciklohexil)

3

H

300

10

H

H

9H

H

î76-178-CH-CH-(CH2

)3-CH3

II

H

H

<CH2)3CH3 (X=N)

H

183-185

12

H

H

pH

H

234-235-ch

2ch?chch,

13

H

H-CH9CH=CHH

250 -252

14

H

H

2 ÇH3

H

253 255-CH-CH-C CH,

2\/h J

15

H

H-CH2CH2CH2CH3-CH-CCH

102-104

16

H

H

<CH?pCH9Br

H ”

194-196

17

H

H-(CH2)3CH2Br

coch2ch3

147-149

18

4-OCH3

H-ch

2ch2oh

159-160

19

H

H-(CH2)3CH2Br-COCH3

168-170

20

H

H

<ch2)^ch3-ch2ch=ch2

138-140

21

H

H-<ch2)3ch3

CH2ÇHCH20H

162 163

OH

22

H

H-<CH2)3CH3-CH?CH9CH?0H

173-175

23

4-OCH3

H-ch2ch=ch2

H

228-229

24

H

3-OCH3-ch2ch=ch2

H

200-201

(nátriumsó) 220—235

25

H

H-ch2 0 .*-*>

H

289-291

26

H

H-CH2CH2 w

H

255-257 (bomlik)

27

H

H

<CH?),,CH?OH

H

186-188

28

H

H-CH9(CH?)a CH=0H?

H

163-164

29

H

H-CH,(CH,)Â CHCH-COCH,

139-141

30

4-Œ3

H

<CH2)2CH2OH

H 3

227-228.5

31

H

H-ch2ch2oh

H

239-240.5

32

H

3-OCH3

ch2ch2oh

H

1/4 H20 (hidrát)

228-229.5

33

4CH3

3-OCflL-CH2CH2OH

H

1/4 H20: 217-219.5

34

4-OCH,

H-ch2ch2oh

H

214-215

35

4-C!

H

<CH2)2CH2OH

H

249.5-25!

36

H

H

<CH2(5CH2 -<f>

H

198-199

37

4-OCH3

H-(CH7),CH90H

H

237-239

38

H

H-(CH2)3CH3-ch2ch3

171-172

39

H

H

<CH2)3CH2OCOCH3-COCH3

161-162

40

H

H-(CH^uCHÎ-ococh2ch3-cch2ch3

119-120

41

4-SCH3

H-(ch^cti,

H

262-263

42

H

H-(CH^CH-OCOCH,-COCH-,

173.5-175.5

43

H

H

<ch2)2ch2--OC(fcH~CH,-coch2ch3

134-136.5

5