152361. lajstromszámú szabadalom • Eljárás egy új polipeptid előállítására

152361 10 CONH2 S—R' C6

H

5

C6

H

5

CH2

CONH2

S—R' CH2

CH2

CH2

CH2

CH2

CH2 R'^NH—OH—CO—NH—OH—CO—NH—CH —CO—NH—OH—CO—MH—OH—OO—WH —CH—<COCys Phe Phe Glu Asp Cys NH—R" CH CH2

— CH2 CH CH2

CH —N CH—CO—JNH-JCH—OO^NH—CH2—CONH

2 Pro Orn Gly (IV) CONH2 SH C6

H

5

CeHs CH2

CONH2

SH I I I I I I CH2

CH2

CH2

CH2

CH2

CH2 I. I I I I I NH2-CH—CO—NH—OH—CO-tfíH—CH —CO—NH—OH—CO—NH—OH—CO—NH —CH—COCys Phe Phe Glu Asp Cys N«2 CH2 CH2—CH2 1 CH2 CH2 1 CH2 1 _N CH—CO—'NH-JCH—-CO—NH—CH2—CONH2 Pro Orn Gly (V)