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napon vizsgált állatokban. Kapilláris technikával végzett vizsgálatok során a MLA fokozta a nem fertőzött állatok lépsejtjeinek in vitro vándorlását. Antigén-mentes tápfolyadékban a fertőzött állatokból izolált lépsejtek migrációja szignifikánsan élénkebb volt a nem fertőzött állatokéhoz viszonyítva. Irodalom 1. BENDIXEN, G. : Személyes közlés. 2. BLOOM, B. R. - BENNETT, B. (1971): The assay of inhibition of macrophage migration and the production of migration inhibitory factor (MIF) and skin reactive factor (SRF) in the guinea pig. In: In vitro methods in cell-mediated immunity. Ed. B. R. Bloom and Ph, R. Glade. Academic Press, New York and London, 235248. 3. CATTY, D. (1969): The immunology of nematode infections. Trichinosis in guinea pigs as a model. Monographs in Allergy 5. 1-134. 4. CYPESS, R. - LARSH Jr. J.E. (1970): The macrophage inhibition assay (MIA) as an in vitro correlate of delayed hypersensitivity (DH) in mice sensitized to Trichinella spiralis antigens (s). J. Parasit. 56. (Sect. II. Part 1) 64-65. 5. CYPESS, R. - LARSH Jr. J. E. - PEGRAM, Ch. (1971): Macrophage inhibition produced by guinea pigs after sensization with a larval antigen of Trichinella spiralis. J. Parasit. _57, 103-106. 6. DAVID, J. R. - DAVID, R. (1971): Assay for inhibition of macrophage migration. In: In vitro methods in cell-mediated immunity. Ed. B. R. Bloom and Ph. R. Glade. Academic Press, New York and London, 249-258. 7. DESPOMMIER, D.D. - MÜLLER, M. (1970): The stichosome of Trichinella spiralis: its structure and function. J.Parasit. 56. (Sect. II. Part 1) 76-77. 8. DUMONDE, D. C. - WOLSTENCROFT, R. A. - PANAYI, G. S. - MATTHEW, M. MORLEY, J. - HOWSON, W. T. (1969): "Lymphokines": non-antibody mediators of ceUular immunity generated by lymphocyte activation. Nature (London), 224. 38-42. 9. GEORGE, M. - VAUGHAN, J. H. (1962): In vitro cell migration as a model for delayed hypersensitivity. Proc. Soc. Exp. Biol. (N. Y. ) 111

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