Fogorvosi szemle, 2015 (108. évfolyam, 1-4. szám)

2015-03-01 / 1. szám

12 FOGORVOSI SZEMLE 108. évf. 1. sz. 2015. 23. Ujpál M, Matos O, BIbok G, Somogyi A, Szigeti K, Szabó G, et al: Diabetes mellitus and tumors of the oral cavity - epidemiologic correlations. Orv Heti! 2004; 145: 755-759. 24. Ujpál M, Matos O, Bíbok Gy, Szabó Gy: A diabetes mellitus elő­fordulása malignus szájüregi daganatos betegekben. Orv Hetil 2002;143:2731-2733. 25. Vairaktaris E, Spyridonidou S, Goutzanis L, Vylliotis A, Lazaris A, Donta I, et ai: Diabetes and oral oncogenesis. Anticancer Res 2007; 27: 4185-4193. 26. Wu CH, Wu TY, Li CC, Lui MT, Chang KW, Kao SY: Impact of diabetes mellitus on the prognosis of patients with oral squa­mous cell carcinoma: a retrospective cohort study. Ann Surg On­­col 2010; 17: 2175-2183. Végh D, Bányai D, Ujpál M The change of the incidence of diabetes mellitus in oral cancer patients based on long-term follow-up studies Our research is focused on the incidence of diabetes mellitus and glucose metabolic disorders among oral cancer pa­tients and the frequency of different oral localizations of cancer. Diabetes mellitus affects 7% of the Hungarian population. This study uses data spanning 14 years, with 2 datasets of 1998-1999 and 2012-2013, collected first hand by the authors. These datasets have led us to examine the blood glucose level in 267 patients with histologically confirmed malig­nant tumours in the oral cavity. Diabetes mellitus was found in 59 of them (22,1%), The blood glucose was elevated in 32 cases (12%). The most frequent tumor locations among the diabetic patients: labial, lingual and gingival tumors gin­givae. Comparative epidemiological study demonstrates that in 2012-2013 dataset there was an increased observed percentage of people with diabetes mellitus [17,6% to 22,1%]. The percentage of patients with IFG (impaired fasting glu­cose) also increased from 9,8% to 12%. Overall the number of patients with glucose metabolic disorders climbed from 27,4% to 34,1%, (p > 0,05). Our intention of this introductory analysis is to emphasize the close connection of these two very important disease groups, and the wider spread of diabetes mellitus. Keywords: diabetes mellitus, oral carcinoma, locations of oral cancer, risk factors

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