202287. lajstromszámú szabadalom • Eljárás humán immun interferon és ezt tartalmazó gyógyszerkészítmények előállítására
HU 202287 B JGAAMI(>GCTATTAGMGS£A/\AG4TCAGTT/WGTCCTrTGGACCTGATCACCTT(jATAC/WÖWC7flCTGATTTCAACTTCTrTGIiCTTAATTCTCTCGGMflCG ATG MA TAT . Io 1ŐQ SLO S20 i 10 thr »er tyr iie leu «1* phe tin leu cyt He viL leu gly »er leu gly CYS TYR CYS GLN ASP PRO TYR VAL LYS CLU ALA CLU ASM ACA AGT TAT ATC TTG GCT TTT CAG CTC TGC AT£ GTT TTG GGT TCT CTT GGC TGT TAC TGC CAG GAC CCA TAT GTA AM GM G£A GM AfiC 150 200 20 30 40 LEU LYS LYS TYR PHE ASM ALA GLY HIS SER ASP VAL ALA ASP ASH GLY THR LEU PHE LEU GLY ILE LEU LYS AS« TRP LYS GLU CLU SER CTT AAG AAA TAT T7T AAT GCA GGT CAT TCA GAT GTA GCG GAT AAT GGA ACT CTT TTC TTA GGC ATT TTG AAG AAT TGG AAA GAG GAG AGT 2?0 50 60 70 ASP ARC LYS ILE MET GLN SER CLN ILE VAL SER PHE TYR PHE LYS LEU PHE LYS ASN PHE LYS ASP ASP CLN SER ILE CLN LYS SER VAL GA£ AGA AM ATA ATG CAG AGC CM An GTC TCC TTT TAC TTC AAA CTT TTT AAA MC ITT AAA GAT GAC CAG AGC ATC CAA AAG AGT GTG 300 350 80 90 100 CLU THR ILE LYS GLU ASP HÉT ASM VAL LYS PHE PHE ASN SER ASN LYS LYS LYS ARC ASP ASP PHE GLU LYS LEU THR ASN TYtt SER VAL GAG ACC ATC AAG GM GAC ATG MT GTC AAG TTT TTC MT AGC AAC AM AAG AM CGA GAT GAC TTC GM AAG CTG ACT AAT TAT TCG GTA 400 4?0 HO 120 130 THR ASP LEU ASN VAL GLN ARC LYS ALA ILE HIS CLU LEU ILE GLN VAL MET ALA CLU LEU SER PRO ALA ALA LYS THR CLY LYS ARC LYS ACT GAC TTG AAT GTC CM CGC AAA GCA ATA CAT GM CTC ATC CM GTG ATG GCT GM CTG TCG CCA GCA GCT AM ACA GGG AAG CGA AM soo 5^0 140 146 STOP ARC SER GIN MET LEU PHE ARC CLY ARC ARC ALA SER GLN AGG AGT CAG ATG CTG TTT CGA GGT CGA AGA GCA TCC CAG TM TGGTTGTCCTGCCTGCMTATTTGMTTTTMATCTAMTCTATTTATTMTATTTAACATTA — 600 650 TrTATATGGGGMTATArmTAGACT£ATCMTCAMTAAGTATTTATMTAGCAACTrTTGTGTMTGAAMTGMTATCTATTMTATATGTATTAnTATMTTCCTATATCCTG 700 7?0 TG/^TGTCT(XnMTCCTnGTTTTCTGACTMnAGGCAAGGCTATGTGATTACAAGGCTTTATCTCAGGGGCCAACTAGGCAGCCAACCTAAGCAAGATCCCATGGTTGTGTGTT •800 850 . 900 TATTTCACTTGATGATACMTGAAC/CTTATAAGTWAGTGATACTATCCAGTTACTGCCGGTTTGAAMTATGCCTGCMTCTGAGCWGTGCTTTMTGGCATGTCAGACAGAACTT 950 1000 GMTGTGTCAGGTGACCCTGATGAAAACATAGCATCTCAGGAGATTTCATGCCTGGTGCTTCCAMTATTGTTGACAACTGT&fiCTGTACCCAMTGÖWGTAACTCATTTGTTAAM 10 50 I too 5. ábra 0184M
