190898. lajstromszámú szabadalom • Antidotumként 8-oxi-kinolin-származékokat tartalmazó készítmények, valamint eljárás a 8-oxi-kinolin-származékok előállítására

19

190.898

20

Hatóanyag

sorszáma

R

í

r2

r3

R,

r5

R,

X

y

175.

H

H

H

H

H

H-CH(CH3)-COS(CH2)„CH3

176.

H

H

H

H

H

H

~CH(CH3)(e)

177.

H

H

H

H

H

H-CH(CH,)-COOCH2CH(OH)-CH2OH

178.

Br

H

Cl

H

H

H-CH(CH,)-coocfi3

179.

H

H

H

H

H

H-CH(CH,)-C00(CH,)6CH3

180.

H

H

H

H

H

H-CH(CH3)-COO(CH2)15CFI3

181.

H

H

H

H

H

H-CH(CH3)-COO(CH2)„ÖH

182.

Br

H

Cl

H

H

H-CH(CH3)-cooc2h<

183.

H

H

H

H

H

H-CH(CH3)(iii)

184.

H

H

H

H

H

H-CH(CH3)-COO(CH2)3CH3

185.

H

H

H

H

H

H-CH(CH,)-C0NH(CH2)5CH,

186.

H

H

H

H

H

H-CH(CH3)(jjj)

187.

H

H

H

H

H

H-CH(CH,)-CONHCH.CHjNHCH.CH.OH

188.

Br

H

Cl

H

H

H-CH(CH3)--COOC.H7izo

189.

H

H

H

H

H

H-CH(CH3)(kkk)

190.

Br

H

Cl

H

H

H-CH(CH3)-conhch3

191.

Br

H

Cl

H

H

H-CH(CH3)-CONH,

192.

Br

H

Cl

H

H

H-CH(CH,)-CON(CH,),

193.

H

H

H

H

H

H-CH(CH,)~

(111)

194.

H

H

H

H

H

H-CH(CH3)(mmm)

195.

H

H

H

H

H

H-CH(CH3)-COOCFFCN

196.

H

H

H

H

H

H-CH(CH3)-CONH(CH,),COOCH,

197.

H

H

H

H

H

H-CH(CH3)-COO-C(CH3),COOC,H3

198.

Cl

H

Cl

H

H

H-CH-COOH

199.

H

H

H

H

H

H-CH(CH3)(nnn)

200.

H

H

H

H

H

H-CH(CH,)(ooo)

201.

H

H

H

H

H

H-CH(CH3)-COOCH2CH2CN

202.

Cl

H

Cl

H

H

H-ch2--cooch2ch2och,

203.

H

H

H

H

H

H-CH(CH3)(PPP)

204.

H

H

H

H

H

H-CH(CH3)(rrr)

205.

H

H

H

H

H

H-CH(CH3)(sss)

206.

H

H

H

H

H

H-CH(CFI3)-CON(CH2CN)2

207.

H

H

H

H

H

H-CH(CF13)-CONH(CH2)l7CH,

208.

Cl

H

Cl

H

H

H-ch2--COOCH,

209.

H

H

H

H

H

H-CH(CH3)-COO(CH,)7CH3

210.

H

H

H

H

H

H-CH(CH3)(ttt)

211.

H

H

H

H

H

H-CH(CH,)(uuu)

212.

Cl

H

Cl

H

H

H-CH-COOC2H5

213.

H

H

H

H

H

H-CH(CH,)-CONH(CH2)7CH3

214.

H

H

H

H

H

H-CHCCHO(vvv)

215.

H

H

H

H

H

H-CH(CH,)-COO(CH2)4CH3

216.

H

H

H

H

H

H-CH(CH,)(xxx)

217.

H

H

H

H

H

H-CH(CH )(yyy)

218.

Cl

H

Cl

H

H

H-ch2~

COOC3H7ízo

219.

H

H

H

H

H

H-CH(CH )(zzz)

220.

Cl

H

Cl

H

H

H-CH2--conh2

221.

H

H

H

H

H

H-CH(CH)(aaaa)

222.

Cl

H

Cl

H

H

H-CH(CH3)-COOH

223.

H

H

H

H

H

FI-CH(CH3)(bbbb)

224.

H

H

H

H

H

H-CH(CH3)--cooch2-c=ch

225.

H

H

H

H

H

H

~CH(CH3)-cooch2ch,(och ch2)3oh

226.

Cl

H

Cl

H

H

H-CH(CH3)-cooch2ch2ocfi3

227.

H

H

H

H

H

H-CH(CH3)--cooch2ch2sch2ch2oh

228.

Cl

H

Cl

H

H

H-CH(CH3)-COOC.H,

229.

H

H

H

H

H

H-CH(CH31--COSCH2COOCH3

230.

Cl

H

Cl

H

H

H-CH(CH3)COOC,H7n

231.

H

H

H

H

H

H-CH(CH3Í(cccc)

232.

Cl

H

Cl

H

FI

H-CH(CH3Í--COOC,H7izo

233.

H

H

H

H

H

H-CH(CH,)(dddd)

234.

H

H

H

H

H

H-CH(CH3)-COOCH2CCl3

235.

H

H

H

H

H

H-CH(CH3)(eeee)

236.

H

H

H

H

H

H-CH(CHj)(ffff)

237.

Cl

H

Cl

H

H

H-CH(CH3)-CON(CH3)2

238.

H

H

J

H

H

H-CH(CH3)-COOH

239.

H

H

Br

H

H

Ch3-CH(CH3)-COOH

240.

Cl

H

Cl

H

H

H-CH(CH,)-CONHC2H5

241.

H

H

J

H

H

H- CH(CH:t)-COOCH2CH2OCH,

242.

H

H

Br

H

H

ch3-CH(CH3)-cooch2ch,och3

Fizikai

állandó

11