189531. lajstromszámú szabadalom • Eljárás alanin-származékok előállítására

189 531

Szám

n

R1 -R2

R3

Mód

szer

MMR spektrum

175

1

—ch3

—CH2—OH

—CíHj

A

3,9-3,0m (6H); l,2d (3H)

176

1

—ch3

—CH2—O-fenil

—QHj

A

7,3-6,7m (9H); 3,9-3,0 (6H); l,2d (3H)

177

1

—ch3

—CH2—O—(4-metil-fenil)

—QHj

A

7,3-6,6m (8H); 3,9-3,0m (6H); 2,3s (3H); l,2d (3H)

178

1

—ch3

—CH2—O—(4-kÍór-fenil)-QHS

A

7,3-6,7m (8H); 3,9-3,Ont (6H); l,2d (3H)

179

1

h2n—

(CH2)4

—CH2—O—(2-metoxifenil)

—ch5

B

7,2-6,4m (8H); 3,9—3,0m + s (9H); 2,4m (2H); 1,7-1,3m (6H)

180

1

h2n—-(CH2)3—

—CH2—O—(4-nitro-fenil)

—c2h5

B

8,2-6,8m (8H); 3,9-3,0m (6H); 2,4m (2H); 1,7-1,3m (4H);

181

1

(CH3)2 ch— —CH2—

- —CH2—O—(4-etoxikarbonil-fenil)

—C2H5

A

7,6-6,8m (8H); 4,2q (4H); 3,9-3,0m (6H); 1,9-1,3m (3H); 1,2t (6H); l,0d (6H)

182

1

—ch3

—CH2—O—(2-metiI-4- klór-fenil)

—C2H5

A

7,2-6,8m (7H); 3,9-3,0m (6H); 2,3s (3H); l,2d (3H)

183

1-ch3

—CH2—O—CH2-fenil-c2h5

A

7,2-6,9m (9H); 4,0s (2H); 3,9-3,0m (6H); 1,3d (3H)

184

1

—ch3

—CH2—O—CH2—(4- klór-fenil)-c2h5

A

7,4-6,9m (8H); 4,0s (2H); 3,9-3,0m (6H); l,2d (3H)

185

1

h2n—-(CH2)4-—CH2—O—CH2(2-metilfenil)

—c2h5

B

7,4-7,0m (8H); 4,0s (2H):

3,9-3,0m (6H); 2,5-2,2d + t (5H); 1,7-1,3m (6H)

186

1

(3) képletű csoport

—CH2—O—CH2—(2- metoxi-fenil)

•

—c2h5

A

7,8-6,4m (14H); 4,0s (2H); 3,8s (3H); 3,9-3,0m (6H); 2,7m (2H)

187

1

H

—CH20—CH2—(4-karbamoil-fenil)-c2h5

A

7,8-7,0m (8H); 6,0bs (2H); 4,0s (2H); 3,9-3,0m (7H)

188

1

HS—CH2—

—CH20—raj—(2-nitrofenil)-c2h5

B

8,2-7,Ont (8H); 4,0s (2H); 3,9-3,0m (6H); 2,3m (2H)

189

1

HS—CH2—

—CH2—O—CH,,—(2- amino-fenil)-c2h5

B

7,2-6,4m (8H); 4,0s (2H); 3,9-3,0m (6H); 2,3m (2H);

190

1

—ch3

—CH2—O—CH(CH3)2

—c,h5

A

3,9-3,0m (7H); l,2d (3H); 0,9d (6H)

191

1

—ch3

—ch2—o—ch2—ch2—-N(CH3)2

—'C.HS

A

3,9-3,0m (8H); 2,4-2,lm +s (8H); l,2d (3H)

192

1-ch3

O H

Il 1

—CH2—0—C—N-fenil

—c2h5

A

7,6-6,9m (9H); 4,0m (2H); l,2d (3H)

193

1-ch3

— CH2—COOH

—H

A

2,1m (2H); l,2d (3H)

194

1-ch3

—CH2—CONH2

—H

F

6,5bs (2H); 2,1m (2H); 1.2d (3H)

195

1-ch3

—CH2—CON(CH3)2

—H

F

3,9-3,0m + 2s (10H); 2,1m (2H); l,2d (3H)

196

1

(3) képletű csoport

H

—CH2—CON-fenil-íH

F

7,8-6,4m (15H); 2,8-2,0m (4H)

—CH2—CON-fenil