171678. lajstromszámú szabadalom • Eljárás azetidin-ecetsav származékok előállítására
R\ •SR2 II.táblázat <• !-Nv /CH5 Br I X COOR3 XXXI. Vegyület száma Rí R* R3 X op. CQ T„ , CHC13 NMR (8 CDC13) (zárójelben kapcsolási állandó Hz-ben) 1. r^-/^ O II O II ©w" —COCH;/ -CH3 11 / —OCOCH 2<Q 137— 1800, 1795, 1740. 0,05—l,60mlOH, 3,80—4,30m4H, 3,90s + 3,98s3H ©w" —COCH;/ 11 / —OCOCH 2<Q 140 °C 4,50 + 4,72ABq(10)lH, 4,29slH, 5,95d(5)lH, 6,25d(5)lH, 7,68m4H. 2. °H O II " II /^\ 3400,1782, 3,00—3,50m4H, 3,50—3,90m4H, 4,38s2H, 4,47s2H, PhOCH2 CN— —COCH 2Ph —CH 2C 6 H 4 N0 2 —N O hab 1720—1680. 5,00—5,34m5H, 5,50d(5) + 5,77d(5)lH[Ca 3 : 2], 6,70—8,25ml5H. 3. O O II H 11 / _N / _ \ N\_/ 3440, 1780, 1700, 0,2—l,3m5H, l,72brs6H, 3,38brs4H, 3,98d(12)2H, PhOCH2 CN— —COCH 2< —CH 2CC1 3 _N / _ \ N\_/ — 1550, 1150. 4,55s2H, 4,75s2H, 4,33—4,70m2H, 5,17—5,58mlH \ _N / _ \ N\_/ 5,72d(5) + 5,92d(6)lH, 6,80—7,53m6H. 4. H O I 11 / . x sárga 3426, 1779, 1695, 0,23—l,27m5H, 3,16—3,59m4H, 3,74—3,94m4H, PhOCH2 CON— —COCH 2< —CH 2C 6 H 4 N0 2 -N O hab 1603, 1145. 4,05d(6)2H, 4,50—4,71m4H, 5,07—5,40m3H, \ -N O 5,80dd(10,5)lH, 6,82—8,33m9H. 5. II f1 —COOCH-/1 \l 3426, 1781, 0,23—l,27m5H, 4,01d(7)2H, 4,27 +4,33d2H, PhOCH2 CN— —COOCH-/1 \l —CH 2C 6 H 4 N0 2 —OH — 1710—1690, 4,55s2H, 5,10—5,35m3H, 5,88d(5)lH, 6,83—7,64 —COOCH-/1 \l 1601, 1148. m7H, 8,22d(9)2H. 6. II * -03 -o 3440, 1780, 1.67brs6H, 3,33brs4H, 4,5m4H, 5,0—5,5m4H, PhOCH2 CN— -03 —CH 2C 6 H 4 N0 2 -o — 1695, 1600. 6,8—8,2ml4H. 7. II1 -03 N/ _ \ 3440, 1781, l,68brs6H, 3,38brs4H, 4,4-^,9m6H, 5,0—5,8m2H PhOCH2 CN— s/ —CH 2CC1 3 N\_/ — 1698, 1600. 6,8—8,2mlOH.
