Dr. Murai Éva - Gubányi András szerk.: Parasitologia Hungarica 27. (Budapest, 1994)

Hoferellus-type development This type of development (Fig. 3) is characteristic of Hoferellus and Myxobilatus species, though certain Myxidium and Chloromyxum species also develop in that way. In the case of Hoferellus-type development no "cyst" formation can be spoken of. The early stages of Hoferellus and Myxobilatus species start to develop in the epithelial cells of organs having efferent ducts, primarily the kidney. The trophozoites infect new epithelial cells, then form secondary, tertiary and quaternary individuals within the primary parasite cell by multiple internal cleavage (Kovács-Gayer et al. 1987, Molnár £xtrapiscî^

e Fig. 3. Hoferellus-type, development. In this type of development, the extrapiscine stage is followed by a relatively long intracellular stage which then continues in a coelozoic development. (1) Extrapiscine development. (2) Actinosporeans floating in water. (3) Sporoplasms released from actinosporeans infect the epithelial cells of fish. (4) The trophozoites continue their development in cells specific of the parasite species, in the epithelium of efferent ducts. In the primary parasite cell located within the attacked epithelial cell secondary, tertiary and even quaternary cells are formed by internal cleavage. (5) After disruption of the host cell, secondary cells change into plasmodia in the lumen of the efferent ducts (ureter, bile duct). (6) From the tertiary cells sporoblasts are formed in the plasmodia. (7) Spores within the plasmodia may develop already in the lumen of the ducts; however, often they develop only in the bladders (gallbladder, urinary bladder). (8) The spores dejected from disrupted plasmodia get to the outworld with the excretions.