Dr. Murai Éva szerk.: Parasitologia Hungarica 11. (Budapest, 1978)

Table 8 Immunoglobulins PEREZ ESANDI (1970) Eluted antibodies from sera of patients with hydatid disease by using immunoadsorbents. The antibodies were found in the IgG, IgM, and IgA classes. SEITANIDIS, ANGELOPOULOS (1971) Employing a radial immunodiffusion technique, noted increases in IgG and IgM in 28 adult patients with hydatid disease, MATOSSIAN, KANE, CHANTLER, BATTY, SARHADIAN (1972) Reported that with nonspecific IF sera, IgG levels remain elevated. IgM and IgA levels diminished after the cyst was removed. HULDT, GUNNAR, JOHANSSON, LANTTO (1973) Reported that in Fenno-Scandia, immunologic responses of Lapps infected with hydatid disease were marginal. A few individuals responded with IgE levels in a radioallergosorbent (RAST) test. IFT and IDT were also very nonspecific. Almost all cases were lung cysts. SORICE, DELIA, CASTAGNARI (1975b) Measured, by radial immunodiffusion, IgE levels in 34 patients with active hepatic and extrahepatic hydatidosis and in 10 subjects with previous hydatidosis and 15 controls. IgE levels higher than 800 Mg/ml were detected in 33 of the 34 cases, 5 of the 10 with previous disease, and in 4 of 15 normal subjects. DESSAINT, BOUT, WATTRE, CAPRON (1975) In a survey of 89 patients with hydatid disease, found high IgE levels by RAST. A purified hydatid antigen was found to be very reactive with IgE antibodies. SORICE, DELIA, CASTAGNARI (1975b) Measured IgE levels in 34 patients with active hydatid infections by quantitative radial immunodiffusion. In 33 of 34, IgE levels were elevated. VERVLOET, CHARPIN, DUMON, QUILICI (19 75) Measured specific IgE antibody by RAST in the serum of patients with hydatid disease. In 20 of 24 cases, IgE was found in the hydatid fluid of the cyst. A significant quantitation correlation exists between the results of the RAST test and positive serology. In 6 of 24 patients with other diseases, false positive reactions were obtained. MATOSSIAN, ALAMI, SALTI, ARAJ (1976) By using radial diffusion methods, measured IgG, IgM, IgA, IgD, and IgE levels in 83 patients with hepatic and pulmonary hydatidosis, 15 postoperative individuals, and 80 controls. IgG was elevated in all patients. IgM and IgA were elevated in pulmonary cases. IgD was normal, and IgE was elevated in 7 of 21 hydatid patients. VERVLOET, DUMON, QUILICI, CHARPIN (19 76) Used the RAST to evaluate 60 patients with hydatid disease for the presence of specific IgE antibody in the serum. Specific hydatid IgE antibody was found in 54 of 60 subjects. Table 9 The Intradermal Test (IDT) ROY, BISWAS, CHATTERJEE, BASU MALLIK (1970) Evaluated the CFT, IDT, and IHAT in India with 25 proven cases of lung cysts. The IDT was positive in 80% in the immediate test and 3 of 5 patients had positive tests for 5 years. The CFT was positive in 60% and the IHAT in 52%. By using one of the three tests as a positive criterion, 88% were correctly serologically diagnosed. WRAY (1970) Reported the IDT to be insensitive in the diagnosis of hydatid disease in Kenya in very chronic infections, TODOROV, YONKOVA, JURUKOVA (1970) Standardized the IDT on the basis of protein content and found a protein content of 40 g/ml for dialized antigens to be best for epidemiologic investigations.