Magyar László szerk.: Orvostörténeti közlemények 133-140. (Budapest, 1991-1992)
KISEBB KÖZLEMÉNYEK — STUDIES AND LECTURES - Raptis, George: Paleopathological Investigation of Osteoporosis with Dual Energy X-ray Absorptiometry
of lateral scan of fourth lumbar (L4): overall = 548, 17, 3.1% (24) 1st Operator (rep) — 552, 22, 4.0% (6) (seq) = 549, 11, 2,0% (6) 2nd Operator (rep) = 550, 21, 3.8% (6) (seq) 541, 9, 1.6% (6) 1 of ventrodorsal scan of L4: overall = 656, 33, 5.0% (24) 1st Operator (repositioning) = 652, 29, 4.5% (6) (sequentially) = 662, 12, 1.8% (6) 2nd Operator (repositioning) = 657, 40, 6.1% (6) (sequentially) = 653, 13, 2.0% (6) BMD of midshaft of right femur: overall = 1 892, 98, 3.6% (24) 1st Operator (repositioning) - 1 898, 68, 2.7% (6) (sequentially) = 1 909, 52, 2.7% (6) 2nd Operator (repositioning) = 1 870, 75, 4.0% (6) (sequentially) = 1895,59,3.1% (6) There was significant agreement between operators in all series of measurements for each site (no mean value differed from a corresponding one by a probability of more than 0.5). Of great interest is the lack of deviation between operators evident in the values of the hip and lateral scans of L4, which ensures high reproducibility of the determination at these important sites. Furthermore, it is to be noted that, as it was made evident by the coefficients of variation, operator-induced variation is insignificant, while correct positioning is crucial for accurate measurements. Sequential determination resulted in coefficients of variation comparable to those reported by the manufacturer (1.0% for right hid and 1.5% for ventrodorsal scan). No significant post-mortem diagenetic changes of mineral content were detected when concentrations in bone were compared to those in adjacent soil (average Mn levels less than 22 ppm, 12). A 0.66 ug/mg Sr/Ca ratio was determined, compatible with the dietary pattern (mainly agricultural origin of constituents) that precedes the medieval period [20]. The increased Zn/Ca ratio (1.42 ug/mg), and Mg level (4519 ppm) indicate an enrichment with animal protein. Thence, it is assumed that no nutritional effect significantly influenced bone density. Lead levels (47 ppm) were relatively high which is typical of classical and post-classical skeletons from Athens. The atomic Ca content was found to be 300 mg/g dry weight (30%) in the right femoral neck, 420 mg/g (42%) at the cortical part of ipsilateral femoral midshaft, and ca. 250 mg/g (25%) in the lumbar spines. Analysis of regression of DÈXA-determined mineral density (logarithmically transformed) to spectrometric calcium content (Ca cont.) gave a straight line, log(DEXA—BMD) = 0.0412 * (Ca cont) + 1.558 (mg/cm 2 ) with Pearson correlation coefficient R2 = 0.935, p = 0.007.
