Antall József szerk.: Orvostörténeti közlemények 92. (Budapest, 1980)

TANULMÁNYOK - Miczbán Izabella: A sejtkép személetének alakulása a XX. században (magyar és angol nyelven)

principle of electronic computers, information must be called addressed from the pro­grammed memory. The programming has primordial importance since just its inadequacy caused the failure of the Cytoanalyzer. The organizer of the programming must dispose of wide practical knowledge and experience. The construction, elaboration and maintenance of the programmes require several partial processes. It means among others the col­lection of data, microscopic controll, the keeping, revision and if necessary moderniza­tion of the rules of classification. The digitized cell images are stocked and put into circulation according the need in the central cytocibernetical laboratories. The elaboration of the algorhithm that is the division of the process into elementary steps in the course of which it is unmistakably defined what to do step by step — the elaboration of this algorhithm is the task of the mathematician. Thus, on behalf of the electroengineer, the physicist-optician, the morphologist and the mathematician not only a simple collaboration but a highly qualified, coordinated cooperation is needed. Digitized cell image analysis is still in an early stage. Concrete results have already been reported, e.g. the known oncocytodiagnostic parameters (e.g. hyperchromasia) were given a numerical sense. Cells being in different functional conditions had not shown any difference with the traditional microscopic examinations while the mathe­matic analysis of these same cells revealed significant differences in the nuclear struc­ture. [1, 2, 23] These observations, experiments, researches have not been concluded so far, no definite judgement could be borne upon them. They may, however, raise the hope that the computer analysis of the cell image may throw light on the deeper connections of structure and function. Our brief survey covered the development of our view on the cell image from Nissl's equivalent image to the algorhithm of cytocibernetics. In the course of abstraction the cell image has lost of its original visuality. Abstraction, however, does not and cannot reject the microscopic picture. It is in organic connection with the microscopic image, is derived from it and its actual goal is that the abstraction lead to a more founded appreciation and explication of the characteristics of the visual picture. The claim for high quality cooperation of different professions with a newly empha­sized predominance of the interdisciplinary principle may give hope for a more integrative scientific conception. LITERATURE Î . Bartels P. H., Bahr G. F., Wayburn S. J., Olson G. B., Taylor J., Wied G. L. : Evaluation of Correlational Information in Digitized Cell Images. Jour, of Histochemistry and Cyto­chemistry 1974, 22, 69—79. 2. Bartels P. H., Wied G. L. : Computer Analysis and Biochemical Interpretation of Micro­scopic Images: Current Problems and Future Directions. Proceedings of the IEEE 1977 65, 252—262. 3. Bernolák K.: A mikroszkóp. (The microscope.) Budapest, 1979. 288—307, 309—326. 4. Diacumachos E. G., Emerson D., Kopac M. J.: Further Development of the Cyto­analyzer. Acta Cytol. 1962, 6, 238—244 5. Diacumachos E. G., Emerson D., Kopac M. J.: Further Development of the Cytoana­lyzer. Acta Cytol. 1962, 6, 423—428 6. Huzella T.: A sejtközösség szervezete. (The organization of the cellular community.; Bp. 1942. 30

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