Fogorvosi szemle, 2013 (106. évfolyam, 1-4. szám)

2013-09-01 / 3. szám

115 FOGORVOSI SZEMLE ■ 106. évf. 3. sz. 2013. 21. Paweletz CP, Ornstein DK, Roth MJ, Bichsel VE, Gillespie JW, Calvert VS, Vocke CD, Hewitt SM, Duray PH, Herring J, Wang QH, Hu N, Linehan WM, Taylor PR, Liotta LA, Emmert-Buck MR, Petricoin EF: Loss of annexin 1 correlates with early onset of tumorigenesis in esophageal and prostate carcinoma. Cancer Res. 2000; 60: 6293- 6297. 22. Wood ZA, Poole LB, Karplus PA: Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling. Scienc. 2003; (300) 650-653. 23. Lu Y, Liu J, Chengzhao L, Wang H, Jiang Y, Wang Y, Yang P, He F: Peroxiredoxin a potential biomarker for early diagnosis of Hepatitis B Virus related liver fibrosis identified by proteomic analysis of the plasma. BMC Gastroenterol. 2010; 10: 115. 24. Hanks SK, Quinn AM, Hunter T: The protein kinase family: con­served features and deduced phylogeny of the catalytic domains. Science. 1998; 241 (4861): 42-52. 25. Cox M, Nelson DR: Lehninger: Principles of Biochemistry (fifth ed.). W H Freeman & Co. 26. Weinberg RA: The Biology Of Cancer. New York, Garland Sci­ence, Taylor & Francis Group, LLC. 757-759. Jancsik VÁ, Márk L, Gelencsér G, Olasz L: Investigation on oral squamous cell carcinoma biomarkers isolated from patients suffering from type-2 diabetes According to the latest epidemiological data the occurrence of oral squamous cell carcinoma has increased recently in the last 4 decades. In spite of the great emphasis and effort in the field of prevention, novel medication therapy, our knowledge has to be enlarged in the development of this serious disease. Recent conducted epidemiological stud­ies and animal experiments have shown that there is a relationship between type-2 diabetes and oral squamous cell carcinoma. Our goal was to screen human saliva samples for possible biomarkers for oral malignancies in diabetic patients. Key words: Proteomics, oral squamous cell carcinoma, salivary biomarkers, type-2 diabetes

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