Fogorvosi szemle, 2009 (102. évfolyam, 1-6. szám)
2009-06-01 / 3. szám
109 FOGORVOSI SZEMLE ■ 102. évf. 3. sz. 2009. for tumor necrosis factor-alpha (TNF-o) in oral lichen planus? J Oral Pathol Med 1996; 25: 219-224. 73. Sugerman PB, Savage NW, Seymour GJ: Phenotype and suppressor activity of T lymphocyte clones extracted from lesions of oral lichen planus. Br J Dermatol 1994; 131: 319-324. 74. Sugerman PB, Savage NW, Xu LJ, Walsh LJ, Seymour GJ: Heat shock protein in oral lichen planus. J Oral Pathol Med 1995; 24: 1-8. 75. SZladek G, Juhász A, Kardos G, SZőke K, Major T, SZiklai I És msai: High co-prevalence of genogroup 1 TT virus and human papillomavirus is associated with poor clinical outcome of laryngeal carcinoma. J Clin Pathol 2005; 58: 402-405. 76. Tar I, Kiss C, Maródi L, Márton I: Oral and dental conditions of children with selective IgA deficiency. Pediatr Allergy Immunol 2008; 19: 33-36. 77. Thornhill MH, Pemberton MN, Simmons RK, Theaker ED: Amalgam-contact hypersensitivity lesions and oral lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003; 95: 291-299. 78. Tremaine R, Adam JE, Orizaga M: Morphea coexisting with lichen sclerosus et atrophicus. Int J Dermatol 1990; 29:486-489. 79. Vainio E, Huovinen S, Liutu M, Uksila J, Leino R: Peptic ulcer and Helicobacter pylori in patients with lichen planus. Acta Derm Veneorol 2000; 80: 427-429. 80. Van Der Meij EH, Mast H, Van Der Waal: The possible premalignant character of oral lichenoid lesions: A prospective five-year follow-up study of 192 patients. Oral Oncol2007; 43: 238-239. 81. Van Der Meij EH, Schepman KP, Van Der Waal I: The possible premalignant character of oral lichen planus and oral lichenoid lesions. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003a; 96: 164-171. 82. Van Der Meij EH, Van Der Waal I: Hepatitis C virus infection and oral lichen planus : a report from the Netherlands. J Oral Pathol Med 2000; 29: 255-258. 83. Van Der Meij EH, Van Der Waal I: Lack of clinicopathologic correlation in the diagnosis of oral lichen planus based on the presently available diagnostic criteria and suggestions of modifications. J Oral pathol Med 2003b; 32: 507-512. 84. Zhao ZZ, Sugerman PB, Walsh LJ, Savage NW: Expression of RANTES and CCR1 in oral lichen planus and association with mast cell migration. J Oral Pathol Med 2002; 31: 158-162. 85. Zhou XJ, Savage NW, Sugerman PB, Walsh LJ, Aldred MJ, Seymour GJ: TCR vß gene expression in lesional T lymphocyte cell lines in oral lichen planus. Oral Dis 1996; 2: 295-298. Dr. Tar I, Dr. Márton I: The oral lichen planus: doubts and evidence Oral lichen planus (OLP) is the oral mucosal form of the lichen ruber planus disease. Its diagnostics is not an easy task. Difficulties exist in diagnosing OLP because there are no fully accepted criteria (neither clinical, nor histological) of the disease. Its etiopathogenesis is also not fully understood. Previous studies concentrated on local factors of the disease such as bad oral hygiene, bad dental condition, and smoking. These studies established that OLP is relatively independent from these factors. Besides local factors, chronic systemic diseases like diabetes and hepatitis of HCV origin were examined. Studies on the parallel occurrence of the OLP with systemic diseases in different populations led to contradictory results. This might strengthen the fact that etiological factors causing the OLP, or worsening the OLP, or playing a role in malignant changes are not the same. Our review would like to provide possible answers to questions concerning OLP. Key words: OLP, etiology, pathology, histology, malignancy