Fogorvosi szemle, 1996 (89. évfolyam, 1-12. szám)

1996-10-01 / 10. szám

VII. táblázat

A „Super Corega”-tartalmú táp fogyasztásának hatása a vérszérum egyes diagnosztikai szempontból fontos összetevőire

Vérszérum

Csoportok

Kontroll

Corega

Ureanitrogén (mmól/1)

5,57±0,62

6,90±1,35*

Kreatinin (pmol/1)

69,1+12,1

66,4±11,6

Húgysav (pmol/1)

62,9±26,7

41,4±5,9**

Glukóz (mmol/1)

6,6±1,0

6,6+0,6

Összes bilirubin (pmol/1)

5,0+0,9

4,4±0,7

Koleszterol (mmol/1)

1,6±0,3

1,42+0,26

Triglicerid (mmol/1)

1,09+0,32

0,80±0,18

AST (ШЛ)

117±36

108+18

*Az eltérés matematikailag szignifikáns (p<0,05) **Az eltérés matematikailag szignifikáns (p<0,02)

Irodalom: 1. Fábián, T., (szerk.): Klinikai fogpótlástan. Medicina, Budapest, 1989. 239. - 2. Hajtman, B.: Bevezetés a matematikai statisztikába. Akadémiai Kiadó, Budapest, 1968. 153. — 3. babarca, C., Paigen, K.: A simple, rapid, and sensitive DNA assay procedure. Anal-Biochem. 102, 344, 1980. - 4. Schacterle, G. R., Pollack, R. L.: A simplified method for the quantitative assay of small amounts of protein in biologic material. Anal-Biochem. 51, 654, 1973. - 5. Zelles, T., Blazsek, J., Tófalvi, A.: Effects of suramin a trypanocidal drug on the rat parotid gland. Zahn-Mund-Kieferheilkd-Zentralbl. 74, 683,1986.

Zelles, T., Fejérdy, P., Kaán, M., Simon, G., Szombath, D., Záborszky, K.: Studies on the General Effects of „Super Corega”.

The main general effects of the intake of a denture fixing adhesive mixed in the food of rats fed in chronic experiment.

This study was performed to investigate the general effects of „Super Corega”, a denture fixing adhesive in young, developing rats. The animals were fed in the experiment by a diet containing „Super Corega” on (1% of diy weight of food) for 3 months. The major salivary glands and the blood sera of these animals were examined. „Super Corega”, administered in this large dose over a long period, did not exert any toxic effect. This fact was based on the analysis of blood serum (Na, K, Ca concentrations, protein, albumin, BUN, creatinine, uric acid, glucose, bilirubin, cholesterol, triglycerid concentrations, AST, ALT, amylase, LDH activities). Among the major salivary glands, no change in the composition of submandibular and sublingual glands were observed. On the other hand, the atrophy of parotic glands was seen, reflected as a decrease in gland wet weight, wet weight/dry weight ratio, DNA and protein content and amylase activity.

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